"Comparative evaluation of root resorption during Piezocision induced and Platelet Rich Plasma (PRP) induced accelerated orthodontic tooth movement-A clinical study"
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- 1.Assess the rate of root resorption with Piezocision induced accelerated orthodontic tooth movement.
研究概览
简要总结
The increased treatment time required for orthodontic therapy is one of the major causes for the increase in the risk of root resorption. Shorter duration of orthodontic treatment is the need of the hour in current practice as huge number of adult patients demand results within a short span of time. As a result, there is an increased number of studies focusing on methods that accelerate orthodontic tooth movement.
Several noninvasive or invasive techniques have been proposed clinically or experimentally for accelerating orthodontic tooth movement. The noninvasive techniques include (a) biomechanical approach such as the self-ligation brackets, (b) physiological approach such as the direct electric current stimulation, the low level laser therapy, vibration or photomodulation and (c) pharmacological approach such as the injection of prostaglandin or relaxin.
Keser and Dibart, introduced the Piezocision technique, a novel minimally invasive technique for accelerated tooth movement. One of the recently used local agents to accelerate the rate of orthodontic tooth movement is platelet-rich plasma (PRP). PRP is defined as an autologous concentration of platelets in a minute volume of plasma. Hence the study is conducted to assess and compare the amount of root resorption in Piezocision and PRP induced accelerated tooth movement.
Hence the need for the present study is to -
1.To assess the rate of root resorption with Piezocision induced accelerated orthodontic tooth movement.
2.To assess the rate of root resorption with Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.
3.To compare the rate of root resorption between Piezocision induced and Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.
4.To draw the clinical inferences from above.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Angle’s class I malocclusion indicated for bilateral maxillary first premolar extraction.
- •2.Male and female patients between the age group of 18 and 45 years.
- •3.Patients with no clinical signs of periodontal diseases.
- •4.Patients with no gingivitis or untreated caries 5.Patients with no history of periodontal therapy.
排除标准
- •1.Previous history of any orthodontic or orthopedic treatment 2.Any bone pathology, ankylosed teeth.
- •3.Patients taking drugs modifying normal bone physiology (i.e., bisphosphonates) on or before a period of 3 months.
- •4.Long term use ofanti-biotics, phenytoin, cyclosporine, anti-inflammatory drugs, systemic corticosteroids and calcium channel blockers.
- •5.Smokers 6.Patients with evidence of bone loss.
- •7.Patient having a pacemaker or any other active implant.
- •8.Patients who have undergone periodontal treatment within three months of baseline examination.
- •9.Systemic disorder that could influence periodontal health.
结局指标
主要结局
1.Assess the rate of root resorption with Piezocision induced accelerated orthodontic tooth movement.
时间窗: 1 month and 6 month
2.Assess the rate of root resorption with Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.
时间窗: 1 month and 6 month
次要结局
- Compare the rate of root resorption between Piezocision induced and Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.(1 month and 6 month)