Glioma stem cell organoids: preclinical model of glioblastoma heterogeneity to explore resistance mechanisms to conventional treatment schedules.

Recruiting

• Conditions: glioma; Primary brain tumor; 10029211

• Registration Number: NL-OMON44469
• Lead Sponsor: MAASTRO Lab

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

• MRI imaging suggestive for glioblastoma
• > 18 years of age

Exclusion Criteria

• Karnofsky index < 70
• Clotting disorders
• Neurosurgical contraindications for gross total resection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intra-and inter organoid genetic and epigenetic heterogeneity that is<br /><br>representative for GM</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>