Postoperative Sensitivity Following Placement with Different Restorative Materials in Vital Posterior Teeth

Phase 4

Completed

• Conditions: Sensitivity, Tooth
• Interventions: Drug: Self Etch Tetric N Bond Universal®; Drug: Activa TM Bioactive Restorative ®; Drug: Tetric N Bond Universal®; Drug: GC Fuji IX, GC, Japan®

• Registration Number: NCT05882760
• Lead Sponsor: Liaquat University of Medical & Health Sciences

Brief Summary

There is a lack of long-term clinical studies comparing different restorative materials; most of the available studies have only looked at class I cavities or examined post-operative sensitivity in non-caries cervical lesions. The purpose of this study is to measure postoperative sensitivity in clinical settings at 3-month intervals for class 1 and 2 direct posterior restoration

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-05-20
• Study First Submitted QC: 2023-05-30
• Study First Posted: 2023-05-31
• Study Start: 2023-06-01
• Primary Completion: 2024-09-30
• Study Completion: 2024-12-31
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-03
• Last Update Posted: 2025-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Either gender Minimum age 18 years, maximum age 40 years. Class I & II Cavity on maxillary and mandibular 1st and 2nd molars. Vital maxillary and mandibular molar teeth that had occlusal contact with antagonist teeth.

Exclusion Criteria

Irreversible Pulpitis diagnosed clinically and radiographically. Class I & Class II cavity of premolars and third molars Patients taking analgesic prior to treatment. History of allergic reaction to any dental material used in the study. History of parafunctional habits (bruxism and/or clenching) Malocclusion

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Self Etch Tetric N Bond Universal®	Self Etch Tetric N Bond Universal®	Cavities in this group will be restored with Conventional Hybrid Composite Restoration bonded with Self Etch Technique using Tetric N Bond Universal®.
Activa TM Bioactive Restorative ®	Activa TM Bioactive Restorative ®	Cavities in this group will be restored with Activa TM Bioactive Restorative ®
Tetric N Bond Universal®	Tetric N Bond Universal®	Cavities in this group will be restored with Conventional Hybrid Composite Restoration bonded with Etch \& Rinse Technique using Tetric N Bond Universal®.
GC Fuji IX, GC, Japan®	GC Fuji IX, GC, Japan®	Cavities in this group will be restored with GC Fuji IX, GC, Japan®

Primary Outcome Measures

Name	Time	Method
Post Operative Sensitivity	3 Months	Sensitivity will be recorded as present when a patient experienced more pain when the cold stimulus is applied on the restored tooth than on the control tooth is assessed using the modified visual analogue scale to any stimulus (occlusal function, cold/hot water, or sweets) every day by the patient until 7 days, then by the clinician on 7 days, 3 months.

Trial Locations

Locations (1)

Institute of Dentistry, Liaquat University of Medical and Health Sciences; 🇵🇰 Hyderabad, Sindh, Pakistan