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Effect of Folic acid on reducing appetite caused by the use of methylphenidate in children with attention deficit hyperactivity disorder

Phase 2
Conditions
Attention Deficit Hyperactivity Disorder (ADHD).
Disturbance of activity and attention
Registration Number
IRCT2016040927304N1
Lead Sponsor
Ahvaz Jundishapur University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
70
Inclusion Criteria

patients aged between 6 to 12 years old; ADHD diagnosing based on DSMIV; clinical need to treat with methylphenidate; not receiving other pharmacological intervention 2 weeks before the intervention; completing consent form; ability to refer for follow up visits
Exclusion criteria: patients with epilepsy and diabetes; cardiovascular disorder; disorder or using drugs that elevate sympathic system activity like Pheochromocytoma; using Pseudoephedrine; psychosis in patient or in their parents; bipolar disorder; using any drugs and supplements which affect weight; low birth weight; history of prematurity; comorbid tourette, celiac, phenylketonuria, autism, mental retardation syndrome; failure to thrive approved in advance by pediatricians; history of severe side effect with the previous use of methylphenidate; mother drug user ;reduced appetite before the study; minor thalassemia

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Appetite score. Timepoint: 0-2-4-6-8 weeks. Method of measurement: questionnaire.
Secondary Outcome Measures
NameTimeMethod
The weight change. Timepoint: 0-2-4-6-8 weeks. Method of measurement: examination of weight.;The BMI change. Timepoint: 0-2-4-6-8 weeks. Method of measurement: examination of weight and height and standard formula.
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