The effect of adding folic acid to the therapeutic diet of patients with mania

Phase 2

• Conditions: mania.; Other degenerative diseases of the nervous system; F30-F39

• Registration Number: IRCT2013031612825N1
• Lead Sponsor: Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

having diagnosis of  BD type 1,2 (DSM-IV-TR); age> 18 years.
Exclusion criteria: mental retardation (IQ<70); pervasive developmental disorders; patients need ECT or physical controlling; contraindication to use of folic acid and folate dependent tumors; pregnancy; substance abuse or dependency since 3 months ago; risk of suicide which needs preventive interventions; weight lower than 30 kg; schizophrenia; medical or neurological disorders ( epilepsy and other seizure disorders); chronic gastrointestinal disorders; allergy to folic acid; renal disorders; use of supplements such as calcium, and D and B vitamins; chronic infection; anemia.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure and compare the response to treatment in study and control groups based on YMRS scale. Timepoint: After two weeks, one month, two months, three months. Method of measurement: by using Young Mania Rating Scale.