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Comparison of folic acid and folate consumption on ovarian reserve parameters and IVF results

Not Applicable
Conditions
infertility.
Female infertility
Registration Number
IRCT20180409039247N7
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Female
Target Recruitment
280
Inclusion Criteria

Infertile women aged 30-40 with poor response or unknown causes of infertility are candidates for IVF

Exclusion Criteria

Infertility due to PCO; endometriosis; tubal and uterine and having causes of male infertility
History of ovarian or pelvic surgery or medical history of chemotherapy or radiotherapy.
Diseases associated with viral infections (hepatitis), tumors, autoimmune diseases, endocrine disorders, metabolic disorders or acute inflammation.
Patients with definite diagnosis of hereditary diseases or family history of hereditary thrombophilic diseases in family or person.
History of multivitamin use

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary outcome: changes in the number of antral follicles. Secondary outcome: changes in FSH, AMH and Inhibin B and checking the level of possible side effects. Timepoint: The results will be evaluated at the beginning of the study and after three months from the start of the study. Method of measurement: To check AFC vaginal ultrasound and to measure FSH, AMH and Inhibin laboratory (blood sample) will be used.
Secondary Outcome Measures
NameTimeMethod
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