Sprint Interval Training on the Endurance, Strength and Velocity Capacities of Healthy Sedentary Subjects
- Conditions
- Sedentary Behavior
- Interventions
- Other: Sprint Interval Training
- Registration Number
- NCT05013021
- Brief Summary
The present study aims to analyse first, the acute effects generated by a single bout of Sprint Interval Training (SIT) and, secondly, the effects of a long-term intervention on sedentary participants.
- Detailed Description
The main goal is to determine the optimal dose of high-intensity exercise that enhances the best physiological adaptations.
The cumulative effects of SIT, will be assessed by a series of measures placed throughout the time-course (before, after the 1st , the 2nd and the 3rd block of SIT). Those measures consist of physiological measurements (VO2max), neuromuscular capacities (force-velocity profile) the autonomic nervous system responses (heart rate variability) and blood markers (lactate, Creatine phosphoKinase (CK), cytokinases, µRNA). Acute effects will be measured in the familiarisation sessions (after short (8 sprints) and long (14 sprints) sets) by performing a battery of neuromuscular, perceptual, and autonomic nervous system tests before and after the single session of SIT.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 23
- untrained healthy (less than 2 hours of sport per week)
- free from muscular, bone or joint injuries
- free from neurologic disease
- taking neuroactive substances that can alter corticospinal excitability
- Heart or respiratory failure.
- Subjects who have taken corticosteroids within 3 months (inhalation, infiltration or history of corticosteroid therapy).
- Pregnant woman
- Subject under guardianship
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Sedentary participants Sprint Interval Training Series of measures placed throughout the time-course (before, after the 1st , the 2nd and the 3rd block of SIT). These measurements consist of physiological measurements (VO2max), neuromuscular capacities (force-speed profile), autonomic nervous system responses (heart rate variability) and blood markers (lactate, CK, cytokinases, µRNA).
- Primary Outcome Measures
Name Time Method oxygen uptake (VO2max) - ml/min/kg At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart consumption oxygen uptake (VO2max) measured on a cycle ergometer
The main objective is to determine at which time frame of sprint interval training blocks, the endurance performance (VO2max) is best.
- Secondary Outcome Measures
Name Time Method Maximum theoretical speed (m/s) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.
Maximum power (W) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.
Creatine Kinase (UI/l) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart Blood sample
heart rate variability (HRV) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart Cytokines (pg/ml) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart Blood sample
muscle microRNA At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart Blood sample
Maximum theoretical force (N.m) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.
Maximum isometric force (N.m) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart It is measured by means of a voluntary maximum contraction test in which the maximum force generated voluntarily is compared to that voluntarily generated force will be compared to that evoked using electrical stimulation of the femoral nerve.
Lactate (mmol/l) At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart Blood sample
Trial Locations
- Locations (1)
CHU de Saint-Etienne
🇫🇷Saint-Étienne, France