Validation of pre-operative 3.0 Tesla H1-MR spectroscopy for assessment of hepatic steatosis as a risk factor for post-operative outcome after hepatectomy

• Conditions: fatty liver; Liver steatosis; 10019654

• Registration Number: NL-OMON30877
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Patients over 18 years of age
Patients who require a liver resection for:
- hepatocellular carcinoma
- colorectal metastasis
- benign tumors

Exclusion Criteria

Patients under 18 years of age
Patients not suitable for surgery in case of co-morbidity
Patients who are pregnant
Patients who require an acute liver resection
Patients who are claustrophobic (MRI scanner)
Patients who have magnetic or radiofrequency sensitive implants (MRI scanner)
Patients with extreme obesity (MRI scanner)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Valdation and quantification of hepatic steatosis with 3.0 Tesla 1H*MRS and<br /><br>correlation with clinical parameters and histological and biochemical analysis<br /><br>of liver biopsies</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>influence of hepatic steatosis on postoperative morbidity and mortality</p><br>