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Kuopio Fall Prevention Study.

Not Applicable
Completed
Conditions
Health Behavior
Accidental Falls
Aging
Registration Number
NCT02665169
Lead Sponsor
Kuopio University Hospital
Brief Summary

This study evaluates the 6 month exercise intervention (Taiji and gym course) combined with free use of communal recreation facilities in fall prevention.

Morbidity, use of social services and health outcomes of aging women in province of Kuopio, Finland are also monitored. The study combines a six months supervised exercise, followed by six months free, but unsupervised, use of recreational facilities and observational period of second year into total of 2 year follow up duration.

Detailed Description

In 2016, a 2-year randomized controlled trial (RCT) will be launched to investigate the effect of exercise on fall risk, injuries and subjective well-being (SWB) in aging women (n=1078) by using municipal sport services in cooperation with the city of Kuopio. The effect of the exercise intervention on functional capacity, muscle strength, bone, body composition, cognitive function, the use of health services and its cost effectiveness will also be studied.

The trial will be carried out on women belonging to the Kuopio Osteoporosis Risk Factor and Prevention (OSTPRE) Study, which is an ongoing population-based prospective cohort study, with a follow-up of 26 years. It investigates life style factors associated with fractures falls, bone mineral density and morbidity in a target population of 14 220 women, now aged between 75-84 year.

The study combines combination of a 2-year fall prevention trial with the 26 years of life style and medical data from the previous OSTPRE follow up to provide meaningful answers whether municipal exercise program can provide cost effective health gain in elderly. In addition, the study aims to answer, who will benefit from the exercise the most and what are the underlying factors explaining efficacy in the women's previous 26 years of lifestyle and medical history. The study will help to develop strategies for societal fall prevention.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
914
Inclusion Criteria
  • Included in the previous Osteoprosis Risk Factors and Prevention (OSTPRE) study follow up protocol, conducted in Kuopio Finland, between 1989-2015.
Exclusion Criteria
  • Unstable angina pectoris, severe pulmonary disease, not self-ambulatory or institutionalized, moderate to severe dementia.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Risk of fallsTwo years

Method of assessment; Personal fall diary. In case of fall, subject records the event into logbook. Outcome: Number of Falls during follow up.

Risk of fallTwo years

Biweekly text message (SMS) question concerning recent falls during last 2 weeks (Reply:Yes/No). In a case of a positive reply, following phone call to the subject to validate the event. Outcome: Number of Falls during follow up.

Secondary Outcome Measures
NameTimeMethod
All cause morbiditytwo years

Methods of assessment; Use of national health care registries and hospital discharge registries. Outcome: Validated morbidity during follow up.

Functional capacitytwo years

Methods of assessment; Timed Get Up and Go Test (TUG). Outcomes; Time consumed the time that a person takes to rise from a chair, walk three metres, turn around, walk back to the chair, and sit down. Outcome: Time consumed in the task (Seconds).

Body compositiontwo years

Method of assessment; Dual X-ray Absorption (DXA) total body scan. Outcomes; body soft tissue and bone mass distribution (g).

Muscle strength and balancetwo years

Methods of assessment; Balance test protocol by using force plate to measure body sway in various positions. Outcomes; velocity and distance of travel by the center of gravity (mm/second).

Life satisfactiontwo years

Methods of assessment; Life satisfaction scale (LS). Outcomes: Units on a Scale

health-related quality of life (HRQoL)two years

Methods of assessment; 15-D self administered measure scale Outcomes: Units on a Scale.

Life orientationtwo years

Methods of assessment; Life Orientation Test (LOT-R) questionnaire Outcomes: Units on a Scale.

Morbiditytwo years

Methods of assessment; Self reported health survey concerning chronic medical conditions. Outcome: Morbidity during follow up.

Depressiontwo years

Methods of assessment; Geriatric Depression Scale (GDS). Outcomes: Units on a Scale

Range of motiontwo years

Methods of assessment; Squatting test. Outcomes; Physical task to squat down, touch the floor with fingertips and get up, without additional support. Outcome: Able/unable to comply (Y/N).

Postural Balancetwo years

Methods of assessment; One leg stand test. Outcomes; Able to maintain static one leg standing position for ten second (Seconds), Outcome: able/unable to comply (Y/N).

Grip strengthtwo years

Methods of assessment; Maximal grip strength by using handheld dynamometer. Outcomes; Maximal muscle force produced (kg).

Leg muscle strengthtwo years

Methods of assessment; isometric leg extension strength in a sitting position with a force plate device. Outcomes; Maximal muscle force produced (kg).

Psychological stresstwo years

Methods of assessment; Perceived Stress Scale (PSS). Outcomes: Units on a Scale.

Psychological stress copingtwo years

Methods of assessment; Brief Resilience Coping Scale (BRCS). Outcomes: Units on a Scale.

Bone mineral densitytwo years

Method of assessment; Dual X-ray Absorption (DXA) measurement in proximal femur. Outcomes; Areal bone mineral density (g/cm2).

Self perceived quality of lifetwo years

Methods of assessment; World Health Organization WHOQOL-BREF. Outcomes: Units on a Scale.

Trial Locations

Locations (1)

Bone and Cartilage Research Unit, Clinical Research Centre, University of Kuopio

🇫🇮

Kuopio, Finland

Bone and Cartilage Research Unit, Clinical Research Centre, University of Kuopio
🇫🇮Kuopio, Finland

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