Impact of Exercise Training on Cardiac Function in Man

Early Phase 1

Completed

• Conditions: Cardiovascular Disease
• Interventions: Behavioral: exercise training

• Registration Number: NCT01881139
• Lead Sponsor: No. 150 Central Hospital of the Chinese People Liberation Army

Brief Summary

The purpose of this study is to monitor the impact of exercise training on cardiac functions and lipoprotein lipids.

Detailed Description

Exercise can increase the mass of left ventricle, which is also called athletic heart. Athletic heart is most frequently encountered as a pathological manifestation of cardiovascular disease, and the early determinants of athelitic remodeling in the general population are largely unknown. We will recruit 45 men aged 18-25 years who will run 5000 meters 2/day for 3 months. caridac function is examined by ECG and echocardiogram, blood pressure, lipoprotein, heart rate, body weight, cardiac troponin will be examined prior to exercise program and 3 months after exercise.

Study Timeline

• Study Start: 2012-12
• Primary Completion: 2013-05
• Study Completion: 2013-05
• Status Verified: 2013-06
• Study First Submitted: 2013-06-12
• Study First Submitted QC: 2013-06-17
• Last Update Submitted: 2013-06-17
• Study First Posted: 2013-06-19
• Last Update Posted: 2013-06-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 46

Inclusion Criteria

• men
• age 18-25 years
• body mass index (BMI) 18-25 kg/m2
• no regular exercise
• no tobacco use
• no current use of prescribed medications
• no self-report of acute of chronic diseases

Exclusion Criteria

• conditions that do not meet the inclusion criteria listed.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
experimental 1	exercise training	men with exercise training for 3 months

Primary Outcome Measures

Name	Time	Method
change of cardiac function at baseline to exercise training for 3 months	baseline to 3 months

Secondary Outcome Measures

Name	Time	Method
change of lipoprotein at baseline to exercise training for 3 months	baseline to 3 months
change of heart rate at baseline to exercise training for 3 months	baseline to 3 months
Change of body weight at baseline to exercise training for 3 months	baseline to 3 months
change of cardiac troponin frome baseline to exercise training for 3 months	baselin to 3 months
Change of blood pressure from baseline to exercise training for 3 months	baseline to 3 months

Trial Locations

Locations (1)

No. 150 Central hospital of Chinese People's Liberation Army; 🇨🇳 Luoyang, Henan, China