Effects of Exercise Training on Cardiac Function and Lipid Metabolism in Mem 18-22 Year Old
Trial Snapshot
- Phase
- Early Phase 1
- Status
- Completed
- Sponsor
- Enrollment
- 46
- Locations
- 1
- Primary Endpoint
- change of cardiac function at baseline to exercise training for 3 months
Study Overview
Brief Summary
The purpose of this study is to monitor the impact of exercise training on cardiac functions and lipoprotein lipids.
Detailed Description
Exercise can increase the mass of left ventricle, which is also called athletic heart. Athletic heart is most frequently encountered as a pathological manifestation of cardiovascular disease, and the early determinants of athelitic remodeling in the general population are largely unknown. We will recruit 45 men aged 18-25 years who will run 5000 meters 2/day for 3 months. caridac function is examined by ECG and echocardiogram, blood pressure, lipoprotein, heart rate, body weight, cardiac troponin will be examined prior to exercise program and 3 months after exercise.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Health Services Research
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 22 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •age 18-25 years
- •body mass index (BMI) 18-25 kg/m2
- •no regular exercise
- •no tobacco use
- •no current use of prescribed medications
- •no self-report of acute of chronic diseases
Exclusion Criteria
- •conditions that do not meet the inclusion criteria listed.
Outcomes
Primary Outcomes
change of cardiac function at baseline to exercise training for 3 months
Time Frame: baseline to 3 months
Secondary Outcomes
- change of lipoprotein at baseline to exercise training for 3 months(baseline to 3 months)
- change of heart rate at baseline to exercise training for 3 months(baseline to 3 months)
- Change of body weight at baseline to exercise training for 3 months(baseline to 3 months)
- change of cardiac troponin frome baseline to exercise training for 3 months(baselin to 3 months)
- Change of blood pressure from baseline to exercise training for 3 months(baseline to 3 months)