Comparison of brain connections post open-surgery or carotid angioplasty through functional Magnetic Resonance Imaging

Not Applicable

• Conditions: Occlusion and stenosis of carotid artery; carotid stenosis; stroke, not specified as hemorrhagic or ischemic; I65.2; C10.228.140.300.200.360

• Registration Number: RBR-83j396
• Lead Sponsor: Instituto de Neurologia e Neurocirurgia de Passo Fundo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-05-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients 18 years old or older; with carotid stenosis above 60% asymptomatic; or patients who had a transient ischemic attack (TIA) with carotid stenosis above 50%; or ulcerated plaque; who agree to participate in the study

Exclusion Criteria

Patients with severe neurological disease such as parkinsonism, dementia, epilepsy, defined cerebrovascular disease, encephalopathy, severe depression; Patients who use drugs that directly affect the central nervous system, which prevent individualized natural responses to the tests

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increase in carotid revascularization compared by resting state functional Magnetic Resonance Imaging between endarterectomy or carotid artery stenting

Secondary Outcome Measures

Name	Time	Method
Cognitive deficits caused by carotid revascularization compared between endarterectomy or carotid artery stenting;Improvement in cognitive outcomes due to carotid revascularization compared between carotid artery endarterectomy or stent procedures;Relationship between transcranial doppler microemboli, assessed by Doppler ultrasound, during carotid revascularization procedures and cognition, assessed through neuropsychological evaluations