Evaluation of comparative efficacy of Panchapallav Gargles versus Betadine Gargles in management of Vrunda(Pharyngitis) in children

Phase 2

Recruiting

• Conditions: Acute pharyngitis, unspecified. Ayurveda Condition: VRUNDAH,

• Registration Number: CTRI/2022/12/048507
• Lead Sponsor: DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH CENTRE

Brief Summary

Pharyngitis is similar to, a condition Vrunda referenced by Charakacharya in Ayurvedic literature. The vitiation of *Pittadosha and raktaprakopa*, which settles in *Mukha (Gala)**pradesh*as mentioned in *Charaka**Sutrasthan,* is the primary cause of this ailment. 17 ailments in *Kanthapradesh* have been described by *Acharya**Sushruta.*

Pharyngitis is similar to *Vrunda*, a condition referenced by Charakacharya in Ayurvedic literature. So,*Ashtang**Hriday*a, has mentioned the *Kavala**Chikitsa*, which provides good relief in *Mukhagat*and *Gala rogas*, to get rid of such a severe sickness. *Kavala* not only soothes the throat (*GalaPradesh)*, but it also precisely heals symptoms such as *Shoth* (inflammation), *Shool* (pain), *Jwara*(fever), and *Aruchi* (anorexia).

Acharya Charakaand Kashyapa have not described *Ekvrinda*and *Vrinda*. Charaka description of the *Galgraha*on the basis of etiopathogenesis may be taken while *Kashyapa*description of the *Galgraha*& *Kantashotha*can be compared with Pharyngitis when evaluatedon the basis of clinical features.Tender cervical lymphadenopathy is also found in viral pharyngitis which can be denoted as *Kanthavedana*.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-12-23
• Study Start: 2023-01-01

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Diagnosed patients of Acute Mild Pharyngitis (Vrunda) between the age of 5 to 14 years presenting with clinical signs and symptoms less than 7 days, given Parent’s consent irrespective of gender, caste, religion & socio-economic background.

Exclusion Criteria

• Known cases of Pneumonia, Bronchial Asthma, Bronchiectasis, Pleurisy, Tuberculosis, Malignancy and other systemic diseases with sore throat.
• Congenital anomalies of Respiratory Tract.
• Participants having Tobacco Addiction, Moderate and Severe grade fever.
• Patient on any other medication.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in hoarseness of voice,soreness in throat (Ruk), Gala Shotha, Daha, Jwara, Suchividdhavatavedna, Kanthkandu,Ragatva(hyperemia)	7 days

Secondary Outcome Measures

Name	Time	Method
Increased oral intake	14 days

Trial Locations

Locations (1)

Mahatma Gandhi Ayurved College Hospital, and Research centre, Salod, Wardha; 🇮🇳 Wardha, MAHARASHTRA, India

Mahatma Gandhi Ayurved College Hospital, and Research centre, Salod, Wardha

🇮🇳Wardha, MAHARASHTRA, India

Dr Riya Rajendra Rathor

Principal investigator

7499128427

riyarathor140395@gmail.com