Phase I Study of Combination Therapy with OBP-301, Atezolizumab and chemoradiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Cancer
Phase 1
- Conditions
- Head and Neck Cancer
- Registration Number
- JPRN-jRCT2063200044
- Lead Sponsor
- Fujiwara Toshiyoshi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
Patients with the oral cavity, oropharynx, larynx, or hypopharynx histologically or cytologically confirmed who are unresectable or wishing organ preservation
- When oropharynx cancer, HPV status is determined
- Definitive chemoradiotherapy of CDDP and IMRT are indicated.
- ECOG Performance Status (PS) is 0 to 1.
Exclusion Criteria
- The stage for primary tumor or cervical nodes is unknown.
- Prior treatment with definitive local therapy or systemic therapy for the head and neck cancer.
- Prior treatment with radiotherapy over the cranial base to clavicle.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method