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临床试验/CTRI/2021/02/031372
CTRI/2021/02/031372已完成不适用

Comparative Assessment of Ayurvedic Properties among the Cultivated Varieties of Ashwagandha (Withania somnifera Dunal) along with their Clinical Evaluation in Grivastambha

Government Ayurved Hospital Vadodara1 个研究点 分布在 1 个国家目标入组 6 人开始时间: 2021年1月5日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
6
试验地点
1
主要终点
Change in the Classical Symptoms of Grivastambha

研究概览

简要总结

This study was randomized clinical trial to evaluate and compare the effects of different varieties of Ashwagandha (Withania somnifera Dunal) in Grivastambha. Total 28 patients were enrolled in 4 groups on the basis of computer-generated randomisation. From those, 24 patients had completed study. In this study powder of four varieties of Ashwagandha was applied with lukewarm water on affected part as a Lepa following Katu Taila Abhyanga twice in a day for 14 days*.* All four varieties of Ashwagandha showed statistically significant difference in various symptoms after treatment. Any ADR was not observed. Highest overall effect of therapy (68.67%) was achieved through Gujarat Anand Ashwagandha-1, while lowest in Nagori Ashwagandha (42.26%). Though, any statistically significant difference was not found among all four varieties of Ashwagandha. Thus, primary outcome that Ashwagandha is effective on Grivastambha was achieved. Along with that secondary outcome was also achieved as difference in clinical efficacy of all four varieties of Ashwagandha on Grivastambha.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant Blinded

入排标准

年龄范围
25.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Clinical symptoms of Grivastambha with or without radiological changes.
  • Pain in the neck Stiffness of neck Difficulty in neck movements (Minimum 3 symptoms) Symptomatology of Grivastambha (cervical spondylosis) for more than 3 months or in recurrent phase.

排除标准

  • <25 Years or >50 Years Any acute/ infectious disease Chronic disease (SLE, rheumatoid diseases, ankylosing spondilitis) Stenosis of the spinal canal Fibrositis Unwilling to participate in the trial.

结局指标

主要结局

Change in the Classical Symptoms of Grivastambha

时间窗: 21 days

次要结局

  • Difference in Clinical efficacy of Cultivated Medicinal Plants Varieties(21 Days)

研究者

发起方
Government Ayurved Hospital Vadodara
申办方类型
Research institution and hospital

研究点 (1)

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