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临床试验/NCT03907761
NCT03907761已完成不适用

Hydrodissection of Recurrent Laryngeal Nerve: Case Series

Ankara University0 个研究点目标入组 34 人开始时间: 2016年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
34
主要终点
mobility of vocal cords preoperative to thyroid surgery

研究概览

简要总结

This study evaluates the hydrodissection technique in recurrent laryngeal nerve (RLN) dissection in thyroid surgeries. In this study hydrodissection of RLN was performed routinely in thyroid surgeries.

详细描述

Thyroid surgery is one of the most frequently performed surgical procedures. Recurrent laryngeal nerve (RLN) injury is the most annoying complication of thyroid surgery. According to literature 0.5-5% and 1-30% of patients is reported to have permanent or temporary RLN injury after the surgery, respectively.

RLN innervates all intrinsic muscles of larynx with the exception of cricothyroid muscle. Injury of RLN causes vocal cord paralysis. Unilateral RLN injury causes hoarseness, but when RLNs are bilaterally damaged aspiration during swallowing or life threatening dyspnea can occur according to severity of glottal narrowing.

Hydrodissection is described in laparoscopic cholecystectomy, cataract surgery, carpal tunnel syndrome treatment where meticulous dissection must be carried out as mentioned above. This technique helps exploring anatomical landmarks by gentle dissection without giving harm to tissues. In thyroid surgery hydrodissection is performed to dissect foamy planes and increase visualization of RLN by high velocity stream of warm saline. Despite being used extensively in routine clinical practice to our best knowledge no report evaluating hydrodissection in thyroid surgery exists in the literature up to date.

In this study, investigators aimed to assess the incidence of RLN damage observed in our series by hydrodissection of RLN during thyroid surgery.

To prevent RLN damage, a good knowledge of anatomy and surgeon's experience are crucial. Routine visualization of RLN along tracheoesophageal sulcus, following the course of RLN near suspensory ligament of berry ligament until entering the larynx is recommended to avoid RLN injury. But still some surgeons declare that visualization of RLN is not possible in all operations. Therefore staying close to thyroid capsule during thyroidectomy is considered to be a good surgical practice to preserve the nerve.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • *patients undergoing thyroidectomy for various thyroid diseases

排除标准

  • * patients in whom RLN palsy detected by indirect laryngoscopy before surgery

结局指标

主要结局

mobility of vocal cords preoperative to thyroid surgery

时间窗: 3 days before surgery

to assess if there is RLN palsy prior thyroidectomy operation preoperative evaluation of vocal cords by indirect laryngoscopy were performed 3 days prior to surgery routinely.

次要结局

  • mobility of vocal cords at the postoperative 3. day(3 days after thyroidectomy)
  • mobility of vocal cord at the injured side(1 month after the operation)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Serkan Akbulut

Principal Investigator

Ankara University

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