Natural History and Patient Journey in Dementia: a Nationwide Linked Electronic Health Records Study of 5.6 Million Individuals.
- Conditions
- Dementia, Alzheimer, Electronic Health Records, Hospitalizations, Epidemiology, Comorbidity, United Kingdom, Incidence, Mortality, Cause of Death
- Registration Number
- NCT04321486
- Lead Sponsor
- University College, London
- Brief Summary
The trajectory of dementia patients within the national health system and their recent temporal trends remains to be fully elucidated. To study the dementia incidence, mortality and case-fatality, we implemented a longitudinal cohort study with the linked electronic health records of 5.6 million population in the UK from 1998 to 2016 (CALIBER). A matched case-control study design was used to investigate the causes of hospitalization and death comparing individuals with and without incident dementia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 4309481
Inclusion Criteria
- We identify individuals aged 30 years or older and registered in the current primary care practice for at least one year.
Exclusion Criteria
- Individuals are excluded if they had a prior history of dementia before study entry.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence and mortality of dementia Jan 1st 1998 - May 31st 2016
- Secondary Outcome Measures
Name Time Method