Comparative evaluation of root coverage procedure using coronally advanced flap with or without resorbable type I collagen membrane for treatment of Miller’s Class I or Class II gingival recession defects: A Randomized clinical trial.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Amount of root coverage
研究概览
简要总结
The rationale for using collagen membranes for guided tissue
regeneration-based root coverage is that it is a natural material which is
biocompatible with the host, its absorbable entity provides a scaffold for tissue
repair while augmenting gingival tissue thickness via in vivo expansion, possessing
a chemotactic function that encourages host cell migration and attachment,
semipermeable allowing gas and nutrient exchange, such characteristics lead to
promotion of clot formation, primary wound closure, better wound stability and
healing, angiogenesis, and clot stability. We hypothesize that coronally advanced flap with resorbable type I collagen
the membrane will positively affect the treatment outcomes of Miller’s Class I or Class
II gingival recession defects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy patients.Presence of gingival recession classified as Millers Class I or II recession defects in upper canines and premolars.
- •Ability to maintain good oral hygiene.
- •Absence of clinical signs of active periodontal disease.
排除标准
- •Patients with known systemic disease.History of prolonged use of antibiotics.Pregnant and lactating women.History of tobacco use in any form.
- •Gingival recession is associated with severe cervical caries.
结局指标
主要结局
Amount of root coverage
时间窗: To be evaluated at baseline, 1 month and 3 months
次要结局
- clinical attachment level gain(width of keratinized tissue)