CNS drug effect profiling in adolescents: an educational class experiment using alcohol as a model. - Alcohol challenge in adolescents.

Centre for Human Drug Research0 个研究点目标入组 16 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

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•Written informed consent from parents having parental responsibility or legal guardian (if subject < 18 years);
•Written informed consent from subject;
•Aged 16-18 (extremes included);
•Attending high school on VWO level;
•Able to communicate with investigator in Dutch;
•Acquainted with effects of alcohol (e.g., use of at least 4 units during the month preceding study participation)

•Any significant medical condition that in the opinion of the medical investigator would be a contraindication for the use of alcohol and/or would interfere with the study objectives;
•Regular alcohol use exceeding an average of more than one unit daily (by medical history);
•Inability to abstain from alcohol for more than 3 consecutive days prior to study days;
•Previously experienced serious adverse event after drinking maximum of 2 drinks per occasion (by medical history);
•Daily use of more than 5 cigarettes (or other nicotine(-containing) equivalent);
•Regular use of illicit drugs (including cannabis); cannabis use exceeding more than 1 intake weekly is considered an exclusion criterion (by medical history);
•Daily use of more than 5 units of xanthine-containing food products or drinks (including but not limited to coffee, tea, energy drinks, chocolate);
•Distaste of orange juice.

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