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临床试验/TCTR20240609004
TCTR20240609004已完成不适用

Contact Investigation for Latent Tuberculosis Infection in Healthcare Workers: Exploring Adverse Events Correlation with NAT2 Genotype

/A0 个研究点目标入组 90 人开始时间: 2024年6月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
90

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 79 Years(—)
性别
All

入选标准

  • Healthcare workers with LTBI at Vajira Hospital who have had significant close contact with patients diagnosed with pulmonary tuberculosis during the 3 months before the index case began treatment, meeting one of the following criteria:
  • 1.Contact with contagious TB for at least 8 hours per day in the same location.
  • 2.Cumulative contact of 120 hours or more per month with contagious TB patients.
  • 3.Exposure to poorly ventilated areas where contagious tuberculosis patients were present and where adequate personal protective equipment (PPE) was not used

排除标准

  • 1. HCWs with a history of contact with patients diagnosed with drug-resistant tuberculosis, viral hepatitis infection, human immunodeficiency virus infection, abnormal liver function tests, related to high access alcohol, active cancer on treatment, unstable myocardial ischemia, heart failure grade 3 or 4, other serious illness, potentially serious drug interactions, history of allergic reaction to isoniazid or rifapentine
  • 2. HCWs deny to participate
  • 3. Incomplete data

研究者

发起方
/A

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