Pilates Physical Activity in Sickle Cell Disease

Not Applicable

• Conditions: Sickle Cell Disease
• Interventions: Behavioral: Pilates training

• Registration Number: NCT05519852
• Lead Sponsor: Cairo University

Brief Summary

Sickle cell anemia (SCA) is a life-threatening hereditary hemoglobinopathy characterized by hemoglobin (Hb) polymerization that affects many people worldwide.Reduced physical capacity is common in people with SCA. Pilates is a form of physical activity that recently used in clinicial practice

Detailed Description

SCA patients (40 patients) with ages more than 18 years will join randomly the pilates group (20 patients) or control non exercised group (20 patients). Pilates will be trained 30 minutes (before it there will be warm up period and after it there will be cooldown period , each will be 5 minutes). the pilates will be repeated five sessions per the week for 3 months

Study Timeline

• Study Start: 2022-06-22
• Status Verified: 2022-08
• Study First Submitted: 2022-08-24
• Study First Submitted QC: 2022-08-25
• Last Update Submitted: 2022-08-25
• Study First Posted: 2022-08-29
• Last Update Posted: 2022-08-29
• Primary Completion: 2022-12-30
• Study Completion: 2022-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• sedentary sickle disease patients from both both sexes in medical stable condition

Exclusion Criteria

• cardiac complaints, pregnant women, patients who smoke or drink alchols

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Pilates group	Pilates training	this pilates group (20 patients) will be trained 30 minutes of pilates (before it there will be warm up period and after it there will be cooldown period , each will be 5 minutes). the pilates will be repeated five sessions per the week for 3 months

Primary Outcome Measures

Name	Time	Method
Pittsburgh Sleep Quality Index	It will be measured after 12 weeks	it assess sleep quality

Secondary Outcome Measures

Name	Time	Method
hand grip strength	It will be measured after 12 weeks	it will assess the muscular strength of dominant hand grip
mental component summary of short-form-36 questionnaire	It will be measured after 12 weeks	it will assess mental health
beck depression inventory	It will be measured after 12 weeks	it is a questionnaire assessing depression
quadriceps strength	It will be measured after 12 weeks	it will assess the muscular strength of dominant quadriceps
physical component summary of short-form-36 questionnaire	It will be measured after 12 weeks	it will assess physical health
six minutes walking distance	It will be measured after 12 weeks	it will assess physical capacity

Trial Locations

Locations (1)

Faculty of Physical Therapy Cairo University; 🇪🇬 Giza, Dokki, Egypt