NCT01169168Unknown不适用
Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome, Sepsis, Chronicle Liver Disease or After Lysis on Intensive Care Units
Johann Wolfgang Goethe University Hospital1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2010年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Fibrinogen levels from 5 test methods
研究概览
简要总结
In this study patients with
- chronicle liver diseases
- primary biliary cirrhosis
- primary sclerosing cholangitis
- alcoholic liver cirrhosis
- hepatitis b or C
- Wilson's disease
- cryptogenic cirrhosis
- Septic Inflammatory Response Syndrome (SIRS)
- sepsis
- septic shock
- patients after lysis
should be included
Blood samples will be gathered from the patients to measure fibrinogen with 5 different methods.
The methods are:
- Clauss fibrinogen
- PT-Derived fibrinogen
- immunoturbidimetric method
- heat-precipitated fibrinogen
- Schulz fibrinogen
The result of these tests will be correlated with laboratory values which are gathered in routine and the clinical outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •septic shock
- •chronicle liver disease (MELD-Score >10)
- •patient after lysis
- •patient agrees
排除标准
- •no agreement
结局指标
主要结局
Fibrinogen levels from 5 test methods
* Clauss fibrinogen * PT-Derived fibrinogen * immunoturbidimetric method * heat-precipitated fibrinogen * Schulz fibrinogen
次要结局
- mortality
- Number of bleedings
- Number of administered thrombocyte concentrates
- Number of administered erythrocyte concentrates
- Number of administered fresh frozen plasma
研究者
研究点 (1)
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