The Application of Lens Dysfunction Index (DLI) in the Timing of Age-related Cataract Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Dysfunctional lens index
研究概览
简要总结
Before cataract surgery, subjects in the observation group used iTrace ocular aberration analyzer(itracey Technologies)and IOL-Master 700 biometer to measure the preoperative DLI(Dysfunctional lens index) and SS-OCT image of the lens, and The researchers used the anterior segment slit lamp to take photos of the anterior segment of the subject's lens in a state of dilated pupils .and self-scoring of the preoperative visual quality assessment scale. Healthy subjects in the control group also need to complete the above inspections. After that, three experienced cataract specialist surgeons combined the preoperative optometry data of each subject, the photos of the LOCS III anterior segment and the Catquest-9SF questionnaire score to determine whether each subjects should undergo cataract surgery. The subjects were divided into cataract surgery group and non-surgical group. Finally, statistically study the correlation between the DLI index and the degree of lens opacity that has been collected, and use the ROC curve to calculate the DLI as the best cut-off point of DLI to distinguish whether to perform cataract surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 40 years old
- •Healthy volunteers with no history of systemic or ocular diseases
- •patients with simple age-related cataracts without other ocular diseases
- •those who can communicate with the tester at a normal level
- •those who can express their own ideas independently
排除标准
- •irregular corneal astigmatism
- •corneal opacity
- •corneal scars
- •corneal dystrophy
- •shallow of anterior chamber
- •retinal abnormalities
- •history of eye surgery or laser treatment
- •pupil diameter less than 4.00mm in a dark environment
- •subjects who did not cooperate well during the examination
结局指标
主要结局
Dysfunctional lens index
时间窗: 2021.01-2021.02
iTrace ocular aberration analyzer(itracey Technologies) to measure the preoperative DLI(Dysfunctional lens index)
次要结局
- SS-OCT image of the lens(2021.01-2021.02)
研究者
Yune Zhao
Deputy Dean
Wenzhou Medical University
