Efficacy and safety of administration of vonoprazan after endoscopic submucosal dissection (ESD) for gastric adenoma/carcinoma
Not Applicable
- Conditions
- Gastric adenoma/carcinoma
- Registration Number
- JPRN-UMIN000018169
- Lead Sponsor
- Chiba University
- Brief Summary
lcer contraction rate at 4 weeks after ESD in the vonoprazan group was significantly higher than that of the esomeprazole group (97.7 +- 3.2% vs 94.5 +- 6.7%, respectively, P = 0.025), and 100% contraction rate tended to be higher in the vonoprazan group relative to the esomeprazole group (32% vs 13%, respectively, P = 0.070).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
Patients evaluated incompetent by doctors in attendance
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of the stage of scar at 4 weeks after endoscopic submucosal dissection (ESD) for gastric adenoma/carcinoma (comparison of vonoprazan and esomeprazole as historical control group)
- Secondary Outcome Measures
Name Time Method The diameter of the ulcer at 4 weeks after endoscopic submucosal dissection (ESD) for gastric adenoma/carcinoma and relationship between these and patients background or lesion information (comparison of vonoprazan and esomeprazole as historical control group)