临床试验/CTRI/2024/06/069049

CTRI/2024/06/069049尚未招募3 期

A study on the effect of Dexmeditomidine on the volume and dose of Propofol required to achieve loss of consciousness using Propofol based Marsh model of target controlled infusion.

Jawaharhal Nehru Medical College1 个研究点分布在 1 个国家目标入组 64 人开始时间: 2024年6月30日最近更新: 2024年6月13日

试验速览

阶段: 3 期
状态: 尚未招募
发起方
入组人数: 64
试验地点: 1
主要终点: volume and dose of propofol

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

A study on the effect of Dexmedetomidine on the volume and dose of Propofol required to achieve loss of consciousness using Propofol based Marsh model of target controlled infusion.

The present study will be undertaken to assess the effect of dexmedetomidine as a pre medicant on the dose and volume of the induction agent -propofol to achieve unconsciousness (loss of eyelash reflex) using Marsh model of TCI.

The secondary objectives are to compare the time required to achieve unconsciousness in both the groups and to study the haemodynamic changes in both the groups.

研究设计

研究类型: Interventional
分配方式: Randomized
盲法: Participant, Investigator and Outcome Assessor Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Patients aged 18-60 years 2)American Society of Anaesthesiologists (ASA) class1-2.

排除标准

•Physical status of ASA class III or more Those with any significant systemic disorders Those with uncontrolled hypertension and cerebrovascular disease Those with co-morbid diseases liver or renal diseases Allergy to the study drugs Pregnant females Preoperative bradycardia less than 55 beats per minute Patients with known history of difficult intubation.

结局指标

主要结局

volume and dose of propofol

时间窗: when there is loss of eye lash reflex

次要结局

1.To compare the time required to achieve unconsciousness in both the groups.(2.To study the haemodynamic changes in both the groups)

研究者

发起方

Jawaharhal Nehru Medical College

申办方类型

Government medical college

责任方

Principal Investigator

主要研究者

Dr Neeraja K R

Jawaharlal Nehru Medical College

研究点 (1)

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