Comparison of the effect of intradermal injection of tranexamic acid versus microneedling plus topical tranexamic acid in the treatment of patients with melasma
Phase 3
Recruiting
- Conditions
- melasma.
- Registration Number
- IRCT20201205049603N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
Having Fitzpatrick II-IV skin type with symmetrical melasma diagnosed by a dermatologist
Patient willingness to participate in the study
Exclusion Criteria
Patients receiving OCP, anticonvulsants, antidepressants, and thyroid medications over the past 12 months
Existence of coagulation disorder or anticoagulant use in the patient
Patient sensitivity to the studied compounds
Existence of active herpes, facial warts or active dermatosis
Pregnancy or lactation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MASI scoring for photographs of patients with melasma. Timepoint: Before the start of the study and 4 weeks after the end of treatment. Method of measurement: MASI score for photography.
- Secondary Outcome Measures
Name Time Method Patient satisfaction with treatment. Timepoint: 4 weeks after treatment. Method of measurement: questionnaire.