The efficacy of Ketamine on treatment-resistant depression's symptoms

Phase 2

Recruiting

• Conditions: Resistant depression.; Major depressive disorder, recurrent, unspecified; F33.9

• Registration Number: IRCT20210125050137N1
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Males and females, aged 18 -65 years old
DSM-V Major Depression Disorder diagnosis confirmed by The Hamilton Depression Rating Scale
The patient has refractory depression, a type of major depression that has not responded to traditional treatment options and the first line of treatment and has taken at least 2 trials of antidepressant drug without sufficient response

Exclusion Criteria

Having other psychiatric illnesses other than major depression
Having a history of one or more seizures for no apparent reason
Pregnancy and lactation
Bipolar disorder
Having uncontrolled non-psychiatric illnesses, including cardiovascular disease
Having a history of stimulant use during the last three months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression score based on Hamilton scale. Timepoint: Monthly. Method of measurement: Hamilton questionnaire.