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Improving Preschool Outcomes by Addressing Maternal Depression in Head Start

Not Applicable
Recruiting
Conditions
Maternal Depression
Interventions
Behavioral: Problem-solving education (PSE)
Behavioral: Usual care
Behavioral: Engagement sessions
Registration Number
NCT04092010
Lead Sponsor
Brown University
Brief Summary

Within a research network of Head Start centers in Massachusetts, an efficacy trial of a stepped-care intervention (SCI) to address maternal depression, using intervention components that both prevent depression and help those in major depressive episode (MDE) engage with care, will be conducted. Both the prevention and engagement components of the model have strong, supportive randomized trial evidence for both their efficacy and safety; but they have yet to be synthesized and tested within a coordinated intervention, applicable to a broad population base. Stepped-care interventions are commonly used in mental health service projects, in which the intensity or type of service is calibrated to the severity of illness.

Detailed Description

This research study is a community-based efficacy trial (n=388) of a stepped-care model intervention to strengthen the capacity of Head Start to address parental depression and related adversities. Head Start mothers with symptoms of depressed mood or anhedonia, and their Head Start children, are enrolled across 12 Head Start centers.

The research study aims to improve developmental outcomes for Head Start children by delivering stepped care intervention that incorporates depression prevention and linkage to formal mental health care to mothers. Mothers with low baseline depressive symptoms are offered a problem-solving intervention while mothers with greater symptoms are offered engagement sessions to link them to formal mental health services. At each problem-solving session participant's symptoms are assessed and if the symptoms meet pre-specified 'step-up' criteria, they are converted to Engagement sessions.

Over 12 months, the intervention's effect will be assessed on a series of outcome measures for mothers; mechanisms by which maternal depression is theorized to impact young children; and child outcomes.

Recruitment & Eligibility

Status
RECRUITING
Sex
Female
Target Recruitment
388
Inclusion Criteria
  • Mother of a 0 to 5-year-old Head Start child
  • Mother speaks English or Spanish
Exclusion Criteria
  • Mother with suicidal ideation
  • Mother with cognitive limitation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Stepped-care intervention (SCI) groupProblem-solving education (PSE)In the SCI group, mothers with low baseline depressive symptoms are offered the problem-solving education (PSE) prevention intervention, and mothers with greater depressive symptoms are offered Engagement Sessions.
Usual care control groupUsual careFamilies in the control group will receive usual Head Start services.
Stepped-care intervention (SCI) groupEngagement sessionsIn the SCI group, mothers with low baseline depressive symptoms are offered the problem-solving education (PSE) prevention intervention, and mothers with greater depressive symptoms are offered Engagement Sessions.
Primary Outcome Measures
NameTimeMethod
Change in incident rates of moderate to severe maternal depressive symptoms based on the QIDSBaseline, 2, 4, 6, 8, 10, 12 months follow-up

The Quick Inventory of Depressive Symptoms (QIDS) will be used to assess the incidence of moderate to severe depressive symptom episodes, as defined by a QIDS score ≥ 11. The QIDS is a 16 item self-administered instrument with potential responses for each item of 0 to 3. Higher scores are associated with greater depressive symptoms.

Change in the mean maternal depressive symptoms based on the QIDSBaseline, 2, 4, 6, 8, 10, 12 months follow-up

The Quick Inventory of Depressive Symptoms will be used to assess depressive symptoms. The QIDS is a 16 item self-administered instrument with potential responses for each item of 0 to 3. Higher scores are associated with greater depressive symptoms. The mean QIDS scores will be calculated for the baseline and each follow up period.

Secondary Outcome Measures
NameTimeMethod
Rate of participants who received evidence-based care defined by psychotherapy or antidepressant medication prescription2, 4, 6, 8, 10, 12 months

The investigators have adapted the services section of the Collaborative Psychiatric Epidemiology Surveys, operationalized into evidence-based care reflecting either psychotherapy or antidepressant medication.

Social Skills Improvement System - Rating Scalesbaseline; 6, 12 months

This valid and reliable scale will be filled out by Head Start teachers. It assesses social skills and problem behaviors for children at risk of interpersonal difficulties.

Bracken School Readiness Assessmentbaseline; 6, 12 months

This scale assesses 85 foundational concepts, including colors, letters, numbers, size/ comparison, and shapes. Assess effect of intervention on child cognitive functioning and school readiness.

Rate of participants who received primary-care based services2, 4, 6, 8, 10, 12 months

The investigators have adapted the services section of the Collaborative Psychiatric Epidemiology Surveys, operationalized into primary care-based services.

Burden of illness for depressionbaseline; 6, 12 months

The Individual Burden of Illness Index for Depression (IBI-D) is a valid and reliable quality of life (QoL) scale, calculated as a composite of the QIDS, the QoL Enjoyment and Satisfaction Questionnaire, and the Work and Social Adjustment Scale

Child absenteeism from Head Startbaseline; 6, 12 months

Head Start centers will furnish us with monthly absentee rates for all families that provide explicit permission. These will be analyzed as count data against day of eligible attendance.

Caregiver-Teacher Report Formbaseline; 6, 12 months

This valid and reliable scale will be filled out by Head Start teachers. It measures emotional reactivity, anxiety/depression, somatic complaints, emotional withdrawal, attention problems, and aggressive behavior.

Perceived Stressbaseline, 4, 8, 12 months

Assess with The Perceived Stress Scale, domains of which include unpredictability, lack of control, burden overload, and stressful circumstances.

Family ConflictBaseline, 6, 12 months

Assess with The 80-item Conflicts and Problem-Solving Scale. Likert scales rate aspects of family conflict known to affect children: 1) number of major and minor conflicts in the past year; 2) family disagreement in 21 areas; 3) frequency of 13 conflict resolution strategies; 4) frequency of 44 conflict tactics.

Behavioral Activation for Depressionbaseline, 4, 8, 12 months

Assess with The Behavioral Activation for Depression Scale (BADS) includes four affective and functional dimensions: activation, avoidance/rumination, work/school impairment, and social impairment.

Coping Strategiesbaseline, 4, 8, 12 months

Assess with The Brief COPE (Coping Orientation to Problems) which measures 14 different adaptive and problematic coping styles. Will also use problem-focused and avoidant subscales.

Parent-Child Interactionbaseline, 6, 12 months

Assess with The Dyadic Parent-Child Interaction Coding System (4th Edition).

Rate of participants engaged with care based on 1 or more psycho/pharmacotherapy visits or psychiatric medication prescriptionBaseline, 2, 4, 6, 8, 10, 12 months follow-up

The investigators have adapted the services section of the Collaborative Psychiatric Epidemiology Surveys, operationalized into engagement with care. This will be defined as ≥ 1 visit for psychotherapy or pharmacotherapy with a behavioral health specialist (social worker, psychologist, psychiatrist, psychiatric nurse); or a prescription for psychiatric medication from any medical practitioner.

Rate of participants retained in care based on 4 or more psycho/pharmacotherapy visits or psychiatric medication prescription2, 4, 6, 8, 10, 12 months

The investigators have adapted the services section of the Collaborative Psychiatric Epidemiology Surveys, operationalized into retention in care. This will be defined as ≥ 4 visit for psychotherapy or pharmacotherapy with a behavioral health specialist (social worker, psychologist, psychiatrist, psychiatric nurse); or a prescription for psychiatric medication from any medical practitioner.

Trial Locations

Locations (1)

Boston Medical Center

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Boston, Massachusetts, United States

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