Salivary Flow Rate and pH during Toothbrushing
- Conditions
- Basic research/Physiological Study - no health conditions under consideration
- Registration Number
- DRKS00026949
- Lead Sponsor
- Zentrum für Zahnmedizin, Universität Zürich, Klinik für Zahnerhaltung und Präventivzahnmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 47
Healthy adult volunteers, 15 males and 15 females. The minimum age requirement has been set at 18 = years of age.
- Persons with salivation rates deviating from predetermined norm values
- Persons who take medication with known effects on salivary flow or intraoral pH value
- Women who are pregnant
- Persons participating in another clinical trial at the same time
- Persons with known allergies or intolerances towards an ingredient in the test toothpastes
- Persons with less than 20 teeth
- Persons wearing any active orthodontic appliances at the time of the study (with the
exception of a dental retainer)
- Persons with any open intraoral wounds
- Persons with dental appointments (dentist or dental hygienist) scheduled less than one day from study trial appointments (Procedures performed during dental appointments may cause intraoral bleeding (for example after periodontal probing), influence salivary flow or intraoral pH (for example through the use of anaesthetics or etching agents)).
- Persons unable to give an informed consent or to follow protocol requirements and procedures
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this research project is to determine pH values of oral fluids and assess the salivary flow rate and subsequent dilution of toothpaste during toothbrushing with toothpastes of various pH values.
- Secondary Outcome Measures
Name Time Method