Improving functional and clinical recovery by combining Individual Placement and Support (IPS) and Motivational Interviewing-based Adherence Therapy (AT) in patients with early psychosis

Phase 4

• Conditions: F31.2; F31.5; F32.3; F33.3; Clinical diagnosis of schizophrenia-spectrum disorders (DSM-V criteria)ICD-10 codes F12.5, F13.5, F14.5, F16.5, F19.5; F20-F29; F30.2; Schizophrenia, schizotypal and delusional disorders; Mania with psychotic symptoms; Bipolar affective disorder, current episode manic with psychotic symptoms

• Registration Number: DRKS00018107
• Lead Sponsor: Otsuka Pharma GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-21
• Study Completion: 2022-11-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

have a stabilised mental disorder in accordance with clinical diagnosis of schizophrenia-spectrum disorders (DSM-V criteria) (contains the following ICD-10 diagnosis: psychotic disorder due to psychoacive substance use F1x.5, schizophrenia, schizotypal and delusional disorders F2x, mania with psychotic symptoms F30.2, Bipolar affective disorder, current episode manic with psychotic symptoms F30.2,5, and severe depressive episode with psychotic symptoms F32.3, F33.3);
- Early Phase of disease: Duration of disease is no longer then 5 years or the first contact due this disease in a medical care Center is no longer than 5 years ago;
- participation in the FRITZ therapy program
- express an interest in competitive employment or professional education;
- sufficient verbal and intellectual skills to participate in the study;
- written consent after enlightenment

Exclusion Criteria

- learning disability (IQ < 70);
- without sufficient German language ability (level a1);
- primary substance abuse disorder;
- physical or organic handicap that seriously impeded work;
- unwillingness to attend regular outpatient treatment;

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of competitive employment or/and mainstream education in the 12-month follow up (monthly evaluation)