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A Comparison of SCH 56592 and Fluconazole in the Treatment of Oropharyngeal Candidiasis (OPC) in HIV-Positive Patients

Phase 2
Completed
Conditions
Candidiasis, Oral
HIV Infections
Registration Number
NCT00002399
Lead Sponsor
Schering-Plough
Brief Summary

The purpose of this study is to compare the safety and effectiveness of SCH 56592 with that of fluconazole in the treatment of OPC (a fungal infection of the throat) in HIV-positive patients.

Detailed Description

This is a randomized, multicenter, double-blind study consisting of 5 arms (4 dose levels of SCH 56592 vs fluconazole) in the treatment of oropharyngeal candidiasis (OPC) in HIV-positive patients.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
500
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (52)

Tucson Veterans Administration Med Ctr

🇺🇸

Tucson, Arizona, United States

Northeast Arkansas Clinic

🇺🇸

Jonesboro, Arkansas, United States

Miami Veterans Administration Med Ctr

🇺🇸

Miami, Florida, United States

Mercy Hosp

🇺🇸

Miami, Florida, United States

Ponce de Leon Med Ctr

🇺🇸

Atlanta, Georgia, United States

Med College of Georgia

🇺🇸

Augusta, Georgia, United States

Rush Med College / Rush Presbyterian - St Luke's Med Cen

🇺🇸

Chicago, Illinois, United States

Wishard Hosp

🇺🇸

Indianapolis, Indiana, United States

Wayne State Univ / Harper Hosp

🇺🇸

Detroit, Michigan, United States

St Michaels Med Ctr

🇺🇸

Newark, New Jersey, United States

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Tucson Veterans Administration Med Ctr
🇺🇸Tucson, Arizona, United States

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