跳至主要内容
临床试验/NCT05193474
NCT05193474Unknown不适用

Evaluate Serious Illness Treatment Preferences and Outcomes in the Patients Receiving Peritoneal Dialysis

National Taiwan University Hospital0 个研究点目标入组 500 人开始时间: 2022年2月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
500
主要终点
the preferences of end of life care in patients receiving peritoneal dialysis

研究概览

简要总结

The goal of this clinical research study is to study the cardiopulmonary resuscitation (CPR) preferences of patients receiving peritoneal dialysis and how these preferences are associated with their responses to questions about aspects of end-of-life care.

This prospective cohort clinical trial aims to provide evidence on the preferences of end of life care in patients receiving peritoneal dialysis, thereby provide optimal care according to patients' preferences and choices through effective communication and clear goals of care.

详细描述

This is a prospective cohort study to survey cardiopulmonary resuscitation (CPR) preferences of patients receiving peritoneal dialysis and how these preferences are associated with their responses to questions about aspects of end-of-life care for end stage renal disease(ESRD) patients, and actively survey their palliative care need to share decision making with ESRD patient whether to receive standardized palliative care interventions by the interdisciplinary palliative care team, including treatment of suffering symptoms, non-pharmacologic therapies. The investigators will enroll 500 patients. The eligibility criteria are shown later part. After obtaining consent from the patient, the investigators will conduct baseline assessments and start the patient on a 10minutes questionnaire. The questionnaire was cited from 2016-CA-POLST, which is in Chinese version for better understanding. POLST is an approach to end-of-life planning based on conversations between patients, loved ones, and health care professionals designed to ensure the patient only receive the care that patients themselves wish to. After that, the investigators will active survey the patient who had higher mortality rate within one year by using 1. Palliative Care Screening Tool (PCST), 2."Surprise" Question,3. Integrated model risk≥10%. For the patient who had higher mortality rate within one year (>10%), the investigators would evaluate the degree of symptoms burden by using ESAS-r: Renal. For the patient who had moderate to severe symptoms burden, the investigators would share decision making with them to discuss whether to receive combined palliative care. The investigators would divide the patients to two group according to patient decision. (1) Usual ESRD care team (2) Usual ESRD care + combined palliative care team. And the investigators would compare the quality of life and quality of death, and symptoms burden after 3/6/12 months receiving timely integrated palliative care to the other group Evaluate outcomes including quality of life (EQ-5D-5L), quality of death (GDS), symptoms burden(ESAS-r:Renal)

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Screening
盲法
None

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • [Patients] Diagnosis of ESRD
  • [Patients] Under treatment of peritoneal dialysis
  • [Patients] Age 20 years or older
  • [Caregivers] Age20 years or older

排除标准

  • [Patients] unable to understand or fill in the questionnaire

结局指标

主要结局

the preferences of end of life care in patients receiving peritoneal dialysis

时间窗: up to 24 weeks

Participants were asked to respond to the questions(POLST questionnaire) associated to life-sustaining treatment preference including CPR preference and other treatment preferences, and life values,

次要结局

  • compare the quality of death after receiving timely integrated palliative care to the other group(3 moths,6 months and 12months after receiving timely integrated palliative care)
  • compare the symptoms burden after receiving timely integrated palliative care to the other group(3 moths,6 months and 12months after receiving timely integrated palliative care)
  • compare the quality of life after receiving timely integrated palliative care to the other group(3 moths,6 months and 12months after receiving timely integrated palliative care)
  • compare the ICU admission frequency after receiving timely integrated palliative care to the other group(3 moths,6 months and 12months after receiving timely integrated palliative care)

研究者

申办方类型
Other
责任方
Sponsor

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