临床试验/NCT03405883

NCT03405883已完成不适用

Comparative Analysis of the Uterine Microbiome in Women With Repeated Implantation Failure and Normal Fertile Women

University Hospital, Ghent1 个研究点分布在 1 个国家目标入组 13 人开始时间: 2018年1月1日最近更新: 2022年12月20日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University Hospital, Ghent
入组人数: 13
试验地点: 1
主要终点: Midluteal uterine microbiome profile

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Characterization of the uterine microbiome in women with repeated implantation failure as well as in normal fertile women.

详细描述

In the midluteal phase of the cycle, a vaginal swab and endometrial biopsy will be obtained.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 39 Years（Adult）
性别: Female
接受健康志愿者: 是

入选标准

•Women between their 18th and 40th birthdays (max 39 years and 364 days at the day of signing the informed consent)
•Able to understand, read and speak Dutch and hence to provide written and oral informed consent
•Negative serological tests for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), Rapid plasma reagin (RPR) for syphilis

排除标准

•Hormonal contraception in current cycle
•Presence of intra-uterine device
•Antibiotic treatment in the current cycle

结局指标

主要结局

Midluteal uterine microbiome profile

时间窗: 1 week

Descriptive analysis of the uterine microbiome present

次要结局

Midluteal vaginal microbiome profile(1 week)

研究者

发起方

University Hospital, Ghent

申办方类型

Other

责任方

Sponsor

研究点 (1)

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