Yoga in the Treatment of Osteoporosis

Not Applicable

Completed

• Conditions: Osteoporosis
• Interventions: Behavioral: Yoga

• Registration Number: NCT02399176
• Lead Sponsor: Manhattan Physical Medicine and Rehabilitation, LLP

Brief Summary

The study measures change in bone mineral density by the DEXA scan before and two or more years after beginning ten minutes of daily yoga designed to put pressure on the spine, hips and femur.

Detailed Description

After collecting blood and urine samples, and pre-study DEXA scans, qualifying patients are given an entry DEXA scan and a DVD with instructions to advance from beginner versions of 12 Iyengar-style yoga poses to more advanced levels in daily practice for 2 years. fter two years or more, subsequent DEXA scans are recorded. Interested participants are also encouraged to have hip and spine X-rays, and bone quality studies on study entry and two years later. Actual subject participation, intercurrent illnesses, fractures and changes in medication are self-monitored with an on line scorecard, supplemented by emails and/or telephone calls when judged necessary by the PI. Results are calculated by change in bone mineral density in the lumbar spine, hips and femurs by the DEXA scan, changes in osteoarthritis according to the X-rays, and changes in bone quality before and two or more years after beginning the ten minutes of daily yoga. Dose-response relationships between the amount and intensity of yoga practice and bone mineral density and quality are sought. Yoga-related fractures and other adverse effects are also noted.

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2015-03-22
• Study First Submitted QC: 2015-03-25
• Study First Posted: 2015-03-26
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2016-01
• Last Update Submitted: 2016-01-10
• Last Update Posted: 2016-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 741

Inclusion Criteria

• Past DEXA scan and, all within 6 months of study entry, DEXA scan and normal values for: Metabolic panel, TSH, PTH, ESR (or CRP), Vitamin D 25 hydroxy, Vitamin D 1,25 dihydroxy, Urine NTX.

Exclusion Criteria

• Known metabolic bone disease such as osteogenesis imperfecta, current treatment with steroids, chemotherapy, or currently healing fractures of lumbar spine, hips or femurs.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Yoga of minimal intensity	Yoga	Does Yoga: At least 4 times/week.

Primary Outcome Measures

Name	Time	Method
DEXA T-score	2 years	Bone mineral density change in spine, hip and femur after 2 years of yoga.

Secondary Outcome Measures

Name	Time	Method
Change in bone quality after doing yoga for two years.	two years
Number of fractures occurring while in study	two years

Trial Locations

Locations (1)

Manhattan Physical Medicine and Rehabilitation, LLP; 🇺🇸 New York, New York, United States