RCT of Cognitive therapy and Schematherapy for comorbid anxiety- and cluster C personality disorders.
- Conditions
- Anxiety Personality disorders co-morbidityangst persoonlijkheidsstoornis comorbiditeit
- Registration Number
- NL-OMON21667
- Lead Sponsor
- eiden UniversityPieter de la Court gebouwWassenaarseweg 522333 AK Leidentel: 071-5274003
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 180
Inclusion Criteria
Patients with an Axis I anxiety disorder (of panic disorder with/without agoraphobia, agoraphobia without a history of panic disorder, obsessive-compulsive disorder, social phobia, generalized anxiety disorder) as primary diagnosis, according to DSM-IV-TR.
Exclusion Criteria
Exclusion criteria are as follows:
1. Evidence of a mental retardation with an IQ less then 70
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method As primary outcome measure significant changes in general anxiety as assessed with the Beck Anxiety Inventory (BAI) (Beck & Steer, 1990) will be used.
- Secondary Outcome Measures
Name Time Method Secondary measures will assess:<br /><br>- more specific forms of anxiety (PSWQ, ASI, FQ, LSAS, PI-R) <br /><br>- general psychopathology (SCL-90R)<br /><br>- interpersonal problems (IIP, WAV)<br /><br>- personality pathology (ADP-IV, NEO-PI-R, NVM)<br /><br>- cognitive schemas and schema modes (SV-1, PDBQ, YPI, YRAI, YCI, SMI-R) <br /><br>- quality of life (WHOQOL-Bref, EQ-6D)<br /><br>- direct and indirect costs (TIC-P) <br /><br>- patient satisfaction (GGZ-thermometer). <br /><br />Remission from anxiety and AXIS II disorder is measured with the MINI and the SCID-II at post treatment and at follow up. Also an implicit computer task will be used to measure the decrease of personality pathology. To evaluate the efficacy of the treatment modalities a cost analysis will be performed using data from a medical consumption diary kept by the patient.