A clinical trial to study the effect of 3 drugs, dexmedetomidine, fentanyl, ketamine in addition to lignocaine nebulization for anesthetizing airway in patients undergoing awake fibreoptic intubation.
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2023/01/049238
- Lead Sponsor
- Yenepoya medical college hospital
- Brief Summary
This study is a randomized, double blind, parallel group, single centre trial comparing the effect of dexmedetomidine(1 mcg/kg), fentanyl( 2 mcg/kg), ketamine( 2mg/kg) in addition to 4 % lignocaine (160mg) nebulization during awake fibreoptic intubation. The primary outcome measures will be the cough score and rate of glottic closure at the time from the starting of intubation till the tube reaches the trachea. The secondary outcomes will be sedation score and to observe for other adverse effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 84
Patients under the category of ASA I/II(American Society of Anaesthesiologist).
1.Previous Airway surgery 2.Anticipated difficult airway 3.Nasal Trauma 4.Allergy to Local Anesthetics.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To determine the cough score. the time from the starting of intubation till the tube reaches the trachea (about 30sec) 2.To determine the rate of glottic closure during bronchoscopy and intubation. the time from the starting of intubation till the tube reaches the trachea (about 30sec)
- Secondary Outcome Measures
Name Time Method 1.To evaluate sedation score. 2.To observe for any other adverse effects.
Trial Locations
- Locations (1)
Yenepoya Medical College Hospital
🇮🇳Kannada, KARNATAKA, India
Yenepoya Medical College Hospital🇮🇳Kannada, KARNATAKA, IndiaDr Smita MustiPrincipal investigator9886125842smitamusti@gmail.com