Detection of Small Fiber Neuropathies by the Non-invasive SUDOSCAN Method During Chronic Autoimmune Pathologies and / or Unexplained Pain Syndromes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Systemic Autoimmune Pathologies
- Sponsor
- Hôpital Européen Marseille
- Enrollment
- 139
- Locations
- 1
- Primary Endpoint
- Percentage of patients presenting diagnosis of small fiber neuropathy in chronic pathologies and / or unexplained pain syndrome
- Status
- Completed
- Last Updated
- 7 months ago
Overview
Brief Summary
Very few studies have evaluated the prevalence of small fiber neuropathy (SFN) during pathologies that may be responsible for small fibers damage.
SUDOSCAN is a new rapid (2 minutes), automated, reproducible and non-invasive technology to assess small fiber neuropathy by sweat function.
With quantitative and reproducible results, SUDOSCAN allows physicians to early detect and follow-up peripheral neuropathy to monitor disease progression and assess treatment efficacy for a better patient management.
SUDOSCAN® could allow the identification of SFN in painful patients apart from another pathology already diagnosed responsible for SFN.
The purpose of the study SUDOCU is to assess the prevalence of small fiber neuropathies (SFN) in patients with systemic autoimmune pathologies or unexplained pain syndrome.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient corresponding to one of the two following groups:
- •Systemic autoimmune pathology known to be complicated by small fiber neuropathies.
- •The following autoimmune pathologies will be included: Lupus, Sjogren, Scleroderma, Myositis, rheumatoid arthritis, Sarcoidosis, Vasculitis of small or medium vessels
- •No conditions known to be responsible at SFN, unexplained pain symptoms
- •Aged ≥ 18 years
- •Having given free and informed written consent
Exclusion Criteria
- •Chronic alcoholism
- •Unbalanced diabetes
- •Chemotherapies
- •Vitamins B12, B1, B6 deficiencies
Outcomes
Primary Outcomes
Percentage of patients presenting diagnosis of small fiber neuropathy in chronic pathologies and / or unexplained pain syndrome
Time Frame: 53 months