Comparison of the effect of dexmedetomidine and propofol on how patients sleep after cardiac surgery

Phase 3

• Conditions: patients with coronary artery disease.; Acute coronary thrombosis not resulting in myocardial infarction; I24.0

• Registration Number: IRCT20161127031131N3
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 118

Inclusion Criteria

cardiovascular surgery aged above 18 years

Exclusion Criteria

If patients received both dexmedetomidine and propofol concomitantly for the primary sedation or an alternative agent as the primary sedation
Prior solid organ transplant
Pregnant patients
Lactating patients

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of patient satisfaction with sedation during intubation. Timepoint: The drugs used will start after patients start to wake up, and 4-6 hours before the time of extubation in both groups .The Richmond Agitation and Sedation Scale (RASS) and Mary's Hospital Sleep Questionnaire used the day after operation in ICU. Method of measurement: The Richmond Agitation and Sedation Scale (RASS) and Mary's Hospital Sleep Questionnaire and vital sign and patients lab data.

Secondary Outcome Measures

Name	Time	Method
The effect of sedation on analgesia after extubation. Timepoint: Based on the Richmond Agitation and Sedation Scale (RASS), and Mary's Hospital Sleep Questionnaire (SMHSQ)which is a valid and reliable method for assessing patient sedation in the intensive care unit. And completing the questionnaire the next day. Method of measurement: Richmond Agitation and Sedation Scale (RASS), and Mary's Hospital Sleep Questionnaire (SMHSQ) and completing a questionnaire on the duration of intubation and intensive care drugs like inoteropes.