跳至主要内容
临床试验/CTRI/2025/04/084822
CTRI/2025/04/084822尚未招募4 期

A Randomized Comparative Clinical Study to Evaluate The Efficacy of Balakulathyadi Kashaya Basti over Dashamoola Ksheera Basti In Pakshaghata with Special Reference to Ischemic Stroke.

Dr Seema Desai1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年4月30日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Improvement in cardinal feature of Pakshaghata (Cheshta Nivrutti

研究概览

简要总结

Pakshaghata is one among the “Vatavyadhi” & is Duschikitsa, Vata is the most powerful Dosha in our body as it responsible for both Maintenance & Vitiation of other Dosha, Dhatu & Mala. The Diseases caused by Vata in its vitiated condition is called

“Vatavyadhi”. There are 80 Nanatmaja Vatavyadhi. Pakshaghata is one among the Vataja Nanatmaja Vyadhi, there will be impairment in Karmendriyas, Gynanendriyas& Manas. Even though Pakshaghata is mentioned in Nanatmaja Vatavikaras of Charaka, it is not only a Shuddha vataja condition there is a samsarga of Pitta and Kapha dosha as mentioned by Sushruta and Madhavakara.The Lakshanas are Cheshta Nivrutti of Vama or Dakshina Parshwa, Ardhakaya Karmahani, Suptata in Hasta and Pada and

Vaksthamba.Kaphanubandha, Pittanubandha, Dhatukshayajanya and Margavaranajanya are the types of Pakshaghata.Acharya Charaka highlighted that “BASTI VATA HARANAM SHRESTA" Basti is a treatment which is considered as “ARDHA CHIKITSA” for Vata Dosha, as it Controls the Vata,Prevent VimargaGamana , does the Sarva Dosha Shamana , Vatanulomana , SrotoShodhana & Shodhana of Doshas from “Pada to Mastishkya”.In the present study Balakulathyadi Kashaya Basti is Planned and Its Ingredients are Bala, Kulatha, Saireyaka, Pippalimoola, Punarnava, Masha, Godhuma, Jeevanti, Suradaru Jaya the properties like Vatahara, Tridosha Shamaka, and few are Anuvasanopaga which is expected to manage the Pakshaghata effectively.

As Dashamoola Ksheera Basti is widely practiced in Pakshaghata. It’s Composition of drug influences Vatanulomana, Balya, Shothahara, Shoolahara, Amapachaka. It is also included in Shotahara Mahakashaya by Acharya Charak.

On the basis of symptomatology of Pakshaghata is compared with Stroke. Stroke is the 2nd commonest cause of Death in India. According to “World Stroke Organization”,

Stroke is a condition where the Blood supply to the Brain is Disrupted, Resulting in Oxygen Starvation of Brain, leading to Brain Damage and Loss of Function.Ischemic Stroke doesdisturbance of focal and global cerebral blood circulation with symptoms lasting 24hours or longer and leading to Death.When Stroke occurs in the main Income earners in the household, there may be enormous consequences for the welfare of the family. The estimated prevalence rate of stroke range is 84-262/100000 in rural and 334-424/100000 Urban, incidence rate 119-145/100000 based on recent population. About 87% of all 1st ever in life time stroke are ischemic, 13% due to primary intra cerebral haemorrhage. Many Subjects retain permanent disability, spasticity and rigidity, because it is very difficult to make complete cure in the management of Pakshaghata. To overcome such conditions an attempt is made to evaluate the efficacy of Balakulathyadi Basti Karma in Pakshaghata.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
30.00 Year(s) 至 70.00 Year(s)(—)

入选标准

  • Loss of Function of Half side of the body with or without Speech Involvement.
  • Pain in either side of the body.
  • Numbness or Weakness of either side of the body.
  • Subjects of either Gender is included.
  • Subjects of age groups between 30 – 70 years are included.
  • Subjects with Ischemic stroke without any severe complications.
  • Subjects fit for Basti Karma.

排除标准

  • Subjects who are disoriented and unconscious.
  • Subjects with Diabetes who are on medication,
  • Blood Pressure equal or above 180/120mm Hg.
  • Pakshaghata complicated with, H/o Intra cranial infections like, meningitis, encephalitis etc.
  • Post traumatic Hemiplegia.
  • Haemorrhagic stroke.
  • Cerebral tumours.
  • Congenital defects such as Arteriovenous malformation, Aneurysm, Diffuse sclerosis, Cerebral agenesis & other major Cerebrovascular anomalies.
  • Subjects suffering with Chronic Kidney Diseases, Acute Kidney Diseases, Congestive Cardiac Failure & Ischemic Heart Disease.
  • Subjects with Acute Ischemic Stroke.

结局指标

主要结局

Improvement in cardinal feature of Pakshaghata (Cheshta Nivrutti

时间窗: After Treatment | 8 days

of Vama and Dakshina parshwa,Vaksanga, Ardha kaya Karmahani,Suptata in Hasta

时间窗: After Treatment | 8 days

and Pada)

时间窗: After Treatment | 8 days

次要结局

  • Assessment of Improvement through stroke scale of national(institute of health,Institute of neurological disorders and stroke (NIH, NINDS) and)

研究者

发起方
Dr Seema Desai
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Seema Desai

Shri D.G.M Ayurvedic Medical College, Hospital PG AND Ph.D. Studies, Research Centre Gadag, Karnatak

研究点 (1)

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