Evaluating use of inhaled dexmedetomidine for pain management in adult burn injury dressing changes
- Conditions
- Pain management in Burn injury patientsAnaesthesiology - Pain managementInjuries and Accidents - Burns
- Registration Number
- ACTRN12623001033639
- Lead Sponsor
- Metro North Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 20
The following 2 groups of patients will be screened for suitability in accordance with the inclusion and exclusion criteria:
1. Patients who are planned to receive conservative treatment (not requiring surgical debridement and grafting) with requirement for regular dressing changes or baths.
2.Patients who have had surgical debridement and grafting and who have had their initial staple removal (typically day 3 or 4 following surgery) with subsequent requirement for regular dressing changes or baths.
Inclusion criteria
•Burn injured patients requiring inpatient care in the Prof Stuart Pegg Adult Burns Unit who are expected to undergo at least two consecutive dressing changes of similar intensity. These dressing changes must not include initial staple removal which tends to be a much more painful and prolonged procedure.
•Age >/= 18 years
•Able to provide consent to participate in the study.
•Able to orally inhale nebulized medications.
Exclusion criteria
1.Temperature >38 degrees C
2.Burns of the face
3.Burns of the lower respiratory tract such that this may impact on drug pharmacokinetics.
4.Systolic blood pressure (SBP) <100 mm Hg
5.Heart rate <60 beats per minute (bpm)
6.Cardiac dysrhythmia
7.Renal failure on dialysis
8.Patients with tracheostomy
9.Allergy to dexmedetomidine
10.Significant mental health disorder or psychological distress
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method