Imaging the Dopamine Systems in Bulimia Nervosa
Completed
- Conditions
- Eating Disorders
- Registration Number
- NCT01493362
- Lead Sponsor
- New York State Psychiatric Institute
- Brief Summary
This study will use positron emission tomography imaging to investigate the dopamine systems in people with bulimia nervosa.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 33
Inclusion Criteria
Participants with BN:
- Meets DSM-IV criteria for BN
- Sufficiently medically and psychiatrically stable to participate in research
Health Control Participants:
- No current or past psychiatric illness
- Between 80% and 120% of ideal body weight
Exclusion Criteria
All participants:
- Current use of psychotropic medication such as anti psychotics or antidepressants
- Pregnant or breastfeeding
- history of substance abuse
- Significant medical illness
- High blood pressure (resting systolic blood pressure greater than 150mmHg and diastolic blood pressure greater that 90 mmHg)
- Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder as defined by DSM-IV
- Metal implants or paramagnetic objects contained within the body that may interfere with the MRI scan, as determined in consultation with a neuroradiologist and according to specified reference book guidelines
- Exposed to radiation in the workplace or has had a nuclear medicine procedure during the 1 year before study entry
- Previous adverse reaction to psycho stimulants
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method D2 receptor density Measured at baseline DA release in the striatum Measures after Mythlyphenidate challenge
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
New York State Psychiatric Institute
🇺🇸New York, New York, United States