The effect of colon cancer on muscle gene expression, body composition, muscle function, and muscle metabolism

Recruiting

• Conditions: (colon cancer) cachexia; body mass losse in cancer patients; muscle loss in cancer patients; 10003018; 10027656

• Registration Number: NL-OMON55854
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Inclusion criteria
CC patients:
In order to be eligible to participate in this study, a subject must meet all
of the following inclusion criteria:
• Diagnosed with primary colon cancer (30) or liver metastases (10)
• Eligible for a tumor resection procedure
Controls:
• Eligible for elective laparoscopic surgery (*, 10; *, 5), for a cause that is
not associated with infections orinflammation, for example cholestectomy
patients, patients undergoing an inguinal hernia repair or an
abdominalhysterectomy

Exclusion Criteria

Exclusion criteria
CC patients:
A potential subject who meets any of the following criteria will be excluded
from participation in this study:
• Having had chemotherapy or an operational procedure of the abdomen in the
past 6 months
• Suffering from malabsorption
Controls:
• Having had treatment for previous or current tumors

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>• Muscle gene expression: transcriptomic analyses of muscle biopsy</p><br>