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Smoking Cessation in Groups and With Tobacco Pastils

Phase 2
Completed
Conditions
Smoking
Registration Number
NCT00265460
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Brief Summary

The purpose of this trial is to examine if smokeless tobacco combined with group support might increase smoking cessation rate compared with groups support in smokers.

Detailed Description

The purpose of this trial is to examine if smokeless tobacco (Oliwer Twist) combined with group support (15-20 per group) might increase smoking cessation rate compared with groups support cold turkey in smokers.The test product should be used for 7 weeks. Seven group meetings are planned during the first 3 months followed bu follow-up sessions after 6 and 12 months. The design is open, randomized. Assessment of ECG, blood pressure, body-weight, carbon monoxide,lung function, stress, quality of life,withdrawal symptoms,adverse events and plasma nicotine, cotinine and thiocyante at entry and after 4 weeks etc.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
240
Inclusion Criteria
  • smoking > 13 cigarettes/day
  • healthy (allowed: hypertension, diabetes type 2, mild asthma/COPD, hypercholesterolemia)
  • motivated for cessation
  • motivated to use tobacco pastils
  • motivated for group support
Exclusion Criteria
  • severe diseases
  • psychiatric diseases
  • using antipsychotic drugs
  • used NRT/bupropion in the last 3 months
  • consuming > 6 drinks/day
  • pregnant/lactating
  • stopped smoking more than 2 days during last 3 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Continuous Smoking cessation quit rate after 6 and 12 months
Secondary Outcome Measures
NameTimeMethod
Side effects from tested tobacco product
Intake of nicotine and thiocyanate

Trial Locations

Locations (1)

Dept. pulmonary medicine Y, Gentofte University Hospital

🇩🇰

Copenhagen, Hellerup, Denmark

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