Breath Analysis to Diagnose Lung Cancer
Not Applicable
Completed
- Conditions
- Lung Cancer
- Interventions
- Device: Collection of volatile organic compounds during exhalation
- Registration Number
- NCT03250390
- Lead Sponsor
- University Hospital, Lille
- Brief Summary
Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1500
Inclusion Criteria
- patients with histologically proven lung cancer
Controls:
- healthy smoker or non-smoker subjects
- without respiratory diseases excepted chronic obstructive pulmonary disease.
Exclusion Criteria
- history of cancer other than lung cancer within 5 years before inclusion
- oral or facial malformation
- incomprehension of maneuvers for the collection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description patients Collection of volatile organic compounds during exhalation Patients with bronchopulmonary cancer who have not yet received therapeutic treatment. controls Collection of volatile organic compounds during exhalation The controls consisted of 2 groups: smokers and non-smokers.
- Primary Outcome Measures
Name Time Method Discriminating power of VOCs 34 months Discriminating power of VOCs using discriminant analyzes using innovative data mining methods based on multi-objective combinatorial optimization.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (7)
Institut Pasteur - Centre de Prévention et d'Education à la Santé (CPES)
🇫🇷Lille, France
Hôpital Calmette, CHU
🇫🇷Lille, France
Hopital Victor Provo
🇫🇷Roubaix, France
Centre Hospitalier de Saint Quentin
🇫🇷Saint-Quentin, France
Chu Amiens Salouël
🇫🇷Salouël, France
Ch Seclin - Seclin
🇫🇷Seclin, France
Clinique Teissier
🇫🇷Valenciennes, France