Breath Analysis to Diagnose Lung Cancer

Not Applicable

Completed

• Conditions: Lung Cancer

• Registration Number: NCT03250390
• Lead Sponsor: University Hospital, Lille

Brief Summary

Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-07
• Study First Submitted QC: 2017-08-10
• Study First Posted: 2017-08-15
• Study Start: 2019-04-29
• Primary Completion: 2024-04-29
• Study Completion: 2024-04-29
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-10
• Last Update Posted: 2025-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• patients with histologically proven lung cancer

Controls:

• healthy smoker or non-smoker subjects
• without respiratory diseases excepted chronic obstructive pulmonary disease.

Exclusion Criteria

• history of cancer other than lung cancer within 5 years before inclusion
• oral or facial malformation
• incomprehension of maneuvers for the collection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Discriminating power of VOCs	34 months	Discriminating power of VOCs using discriminant analyzes using innovative data mining methods based on multi-objective combinatorial optimization.

Trial Locations

Locations (7)

Institut Pasteur - Centre de Prévention et d'Education à la Santé (CPES); 🇫🇷 Lille, France

Hôpital Calmette, CHU; 🇫🇷 Lille, France

Hopital Victor Provo; 🇫🇷 Roubaix, France

Centre Hospitalier de Saint Quentin; 🇫🇷 Saint-Quentin, France

Chu Amiens Salouël; 🇫🇷 Salouël, France

Ch Seclin - Seclin; 🇫🇷 Seclin, France

Clinique Teissier; 🇫🇷 Valenciennes, France