se of Simvastatin Gel for the treatment of Peri-implantitis

Phase 2

• Conditions: periimplantitis; C07.465.714

• Registration Number: RBR-3bqywp7
• Lead Sponsor: niversidade Estadual Paulista, Faculdade de Odontologia de Araraquara, FOAR-UNESP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2024-02-26
• Study Start: 2024-03-07
• Last Update Posted: 2 April 2024

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Greater than or equal to eighteen years of age; greater than or equal to three radiographic bone loss ; greater than or equal to six millimeters of probing pocket depth with bleeding on probing; less than or equal to twenty percent of plaque index; less than or equal to twenty percent of gingival index ; formal consent to participate in the research

Exclusion Criteria

Presence of uncontrolled systemic alteration; use of medications six months prior to the study that may influence the response to treatment; pregnant and lactating women, performing peri-implant treatment including subgingival instrumentation in the six weeks prior to the study; implants with mobility; oral pathology; history of allergy to any component of the study

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find a gain in radiographic bone filling of at least 1mm through linear measurements using the implant platform and the bottom of the defect as reference points using the ImageJ program.

Secondary Outcome Measures

Name	Time	Method
It is expected to find a reduction on probing pocket depth of at least 1mm through clinical measurements using a periodontal probe from gingival margin to the bottom of the implant pocket as reference points.