Immediate Effects of Postural Drainage With or Without Thoracic Squeezing on Oxygen Saturation and Respiratory Rate in Children With Respiratory Distress Syndrome.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Oxygenation levels
研究概览
简要总结
This study investigated whether adding thoracic squeezing to postural drainage improves immediate respiratory outcomes in preterm infants with Respiratory Distress Syndrome (RDS).
Over nine months, 14 preterm infants (all born via cesarean section) were randomly assigned to two groups. The control group received standard care with postural drainage, while the experimental group received postural drainage combined with the lung squeezing technique (LST), which applies gentle chest pressure to enhance airflow and mucus clearance. Infants with genetic disorders, congenital anomalies, or on neurotropic drugs were excluded.
Oxygen saturation and respiratory distress were measured using the Oxygen Saturation Index and Silverman-Anderson Scale, with data analyzed in SPSS.
The study aimed to determine whether combining thoracic squeezing with postural drainage has a greater immediate effect on improving oxygen levels and reducing respiratory distress compared to postural drainage alone.
详细描述
Respiratory distress syndrome (RDS) is a common respiratory condition affecting preterm infants, characterized by insufficient lung function leading to impaired oxygenation and increased respiratory effort. Physiotherapy interventions like postural drainage are often used to improve lung clearance and respiratory status. However, the effectiveness of combining postural drainage with thoracic squeezing on immediate respiratory outcomes remains unclear. The lung squeezing technique (LST), an advanced form of chest physiotherapy, involves applying gentle, sustained pressure to the chest wall, followed by a full release. This process helps elevate intrathoracic pressure, which can activate the cough reflex, aid in the movement of mucus, promote deeper inhalation, and enhance ventilation within the alveoli. The objective of the study is aimed to evaluate the immediate effects of postural drainage with or without thoracic squeezing on oxygen saturation and respiratory rate in children with RDS.
This study was conducted over nine months at AMTH and HLTH settings, enrolling a total of 14 preterm infants with a history of cesarean section birth. Participants were selected using the Epi tool for sample size calculation and randomized into two groups: the control group received standard care involving postural training, while the experimental group underwent postural drainage combined with thoracic squeezing techniques. Exclusion criteria included infants under treatment with neurotropic drugs, those diagnosed with genetic disorders, and those presenting with congenital cardiac or respiratory anomalies. Data collection employed the Oxygen Saturation Index to measure oxygen levels and the Silverman-Anderson Scale to assess respiratory distress. Collected data were analyzed using SPSS software to determine the effects of the interventions on oxygen saturation and respiratory rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
盲法说明
PARTICIPANTS WILL GET SEPARTAE TREATMENT PROTOCOLS, AND POSSIBLE EFFORTS WILL BE PUT TO MASK BOTH GROUPS ABOUT THE TREATMENT.
入排标准
- 年龄范围
- 1 Month 至 2 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •● Children diagnosed with RDS.
- •Pre term infants. Birth history with c- section.
- •No congenital malformation.
排除标准
- •● Under treatment with neurotropic drugs.
- •Respiratory and cardiac congenital anamolies.
- •Genetic disorder.
- •Interventricular hemorrhage or seizures.
研究组 & 干预措施
Oxygenation levels
Evaluated using measures such as pulse oxygen saturation (SpO2) or arterial oxygen saturation (SaO2), arterial partial pressure of oxygen (PaO2), or the Oxygen Saturation Index (OSI). This calculation provides a non-invasive measure of oxygenation efficiency. Research has shown that OSI is just as reliable as the Oxygenation Index (OI) in evaluating the severity of pediatric acute respiratory distress syndrome (PARDS). Since OSI uses peripheral oxygen saturation (SpO₂) instead of arterial blood gases, it serves as a practical and effective alternative, particularly in settings where frequent arterial sampling is not feasible.
The Oxygen Saturation Index (OSI) is determined using the formula:
(FiO₂ × mean airway pressure × 100) ÷ SpO₂ (14).
干预措施: POSTURAL DRAINAGE TECHNIQUE (Other)
ANDERSON Scale.
The Silverman-Anderson scores are widely used clinical tools designed to evaluate the severity of respiratory distress in newborns. Both systems rely on objective clinical parameters to quantify respiratory difficulty. The Silverman-Anderson score specifically measures five key signs: chest retractions in the upper and lower thorax, subxiphoid retraction, nasal flaring, and audible grunting during exhalation. Each of these indicators is rated on a scale from 0 to 2, allowing healthcare providers to systematically assess and monitor the progression or improvement of respiratory distress in neonates.
干预措施: POSTURAL DRAINAGE TECHNIQUE (Other)
结局指标
主要结局
Oxygenation levels
时间窗: BASE LINE, 4 WEEKS
Evaluated using measures such as pulse oxygen saturation (SpO2) or arterial oxygen saturation (SaO2), arterial partial pressure of oxygen (PaO2), or the Oxygen Saturation Index (OSI). This calculation provides a non-invasive measure of oxygenation efficiency. Research has shown that OSI is just as reliable as the Oxygenation Index (OI) in evaluating the severity of pediatric acute respiratory distress syndrome (PARDS). Since OSI uses peripheral oxygen saturation (SpO₂) instead of arterial blood gases, it serves as a practical and effective alternative, particularly in settings where frequent arterial sampling is not feasible. The Oxygen Saturation Index (OSI) is determined using the formula: (FiO₂ × mean airway pressure × 100) ÷ SpO₂ (14).
次要结局
- ANDERSON Scale(BASE LINE, 4 WEEKS)