Randomised, blinded, comparison of the respiratory depressant effects of morphine and S(+) ketamin infusions when used to provide postoperative analgesia in infants undergoing major surgery

Completed

• Conditions: Post operative pain; Surgery

• Registration Number: ISRCTN99206122
• Lead Sponsor: Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

70 infants aged less than 60 weeks post-conceptual age undergoing elective or urgent abdominal surgery who would not be expected to require postoperative artificial ventilation.

Exclusion Criteria

1. Patients with severe CNS abnormalities
2. Patients with severe renal or hepatic dysfunction
3. Patients with post-conceptual age of <37 weeks
4. Patients requiring respiratory support preoperatively
5. Patients receiving epidural opioids or local anaesthetic drugs
6. Patients having apnoeas or periodic breathing preoperatively

Study & Design

• Study Type: Interventional
• Study Design: Not specified