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Comparing Negative Pressure Wound Therapy with Instillation vs. Standard wound care to treat postoperative wound infections

Conditions
SSI, POWI
Registration Number
NL-OMON19878
Lead Sponsor
ZONMW
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
446
Inclusion Criteria

•Age equal or older than 18 years;
•A superficial or deep surgical site infection plus a wound dehiscence (> 5 cm dehiscence) or a wound that needs to be opened for drainage of surgical site infection after any type of surgery;
•Surgical site infeciton occurring within 30 days after surgery;
•A minimum wound size of 10 cm² to allow proper application of the study treatments;
•Written informed consent.

Exclusion Criteria

•A deep organ/space surgical site infection without a superficial (involvement of skin and fascia) wound infection
•Psychically or mentally inability for informed consent
•Fascial dehiscence > 0,5 cm
•Malignancy in the wound
•Untreated osteomyelitis
•Enteric fistula
•The wound located where there is a risk of unintented fluid delivery to the thoracic or abdominal cavity.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time to complete wound healing, defined as re-epithelization of the total wound surface or if the wound is ready for secondary surgical closure (i.e., healthy red granulation tissue without signs of infection or debris).
Secondary Outcome Measures
NameTimeMethod
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