Developing new tests to monitor patients with eosinophilic oesophagitis using capsule sponge instead of endoscopy

Not Applicable

• Conditions: Eosinophilic oesophagitis (EoE); Digestive System

• Registration Number: ISRCTN14071734
• Lead Sponsor: Cyted Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-02-23
• Last Update Posted: 18 March 2024
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

1. Over 18 years old with a histologically confirmed diagnosis of EoE
2. Male or Female
3. Newly diagnosed patients with EoE or known existing non-stenotic EoE patients who are on maintenance treatments (i.e., orodispersible budesonide, PPI, biologics, or dietary therapy) and monitoring
4. Patients currently enrolled in the CoSIE study (IRAS 314770) may be retrospectively included with consent

Exclusion Criteria

1. Age <18 years
2. Strictures or severe rings at most recent endoscopy that prevent passage of adult 9.8 mm gastroscope
3. Oesophageal dilatation within 24 months of clinic visit
4. Previous oesophageal perforation or surgical resection
5. Oesophagogastric malignancy
6. Oesophageal varices
7. Bolus obstruction since last endoscopy requiring hospital visit
8. Previous fundoplication or complicated hiatus hernia
9. Patient on warfarin with INR>=3

Study & Design

• Study Type: Interventional
• Study Design: Not specified